Not much to say about this one, unfortunately. The Gamecocks are missing the two best players on Defense, Bryson Allen-Williams and D.J. Wonnum, and the secondary is still injury-riddled beyond all reasonable expectations. With their talent at the skill positions Clemson will be able to get the ball in space and score on nearly every possession. The good news is that the Offense has a chance to at least score some points this year.
I hate picking against the Gamecocks in this game above all others, but while Muschamp is doing a great job closing the talent gap, SC is still just too far away.
Prediction: USC 31 - Clemson 52. Miss Teriyaki Chicken is the optimist again, and has the Gamecocks winning 35 - 33.